| Wednesday, 18 January, 2017 | |
| All Day | Exhibit Setup |
| 10:00 – 19:00 | Registration Open |
| 10:00 – 19:00 | Poster Setup |
| 18:00 – 19:00 | Welcome and Opening Remarks Joseph Jankovic (USA) Alberto Albanese (Italy) Lifetime Achievement Award Ceremony Recipient: Mark Hallett (USA) |
| 19:00 – 19:30 | Dasgupta Memorial Lecture Cesare Montecucco (Italy) |
| 19:30 – 22:00 | Welcome Reception |
| Thursday, 19 January, 2017 | |
| 07:00 – 18:30 | Registration/Information |
| 07:00 – 08:30 | Exhibits |
| Plenary Session |
|
| 08:30 – 08:40 | Welcome and Opening Remarks and Introduction of Keynote Speaker Andreas Rummel (Germany) |
| 08:40 – 09:30 | Keynote Presentation – Presynaptic Functions Erik M. Jorgensen (USA) |
| 09:30 – 10:00 | Assembly and Disassembly of the SNARE Complex Axel Brunger (USA) |
| 10:00 – 10:30 | What’s the Best Dosage and Interval for BoNT Injections in Dystonia and Spasticity Treatment? Jorg Wissel (Germany) |
| 10:30 – 11:00 | Break |
| 11:00 – 11:30 | Recent Developments in Clinical Trials of BoNT Alberto Albanese (Italy) |
| 11:30 – Noon | Advances in the Architecture of the BoNT Complex Rongsheng Jin (USA) |
| 12:00 – 13:30 | Lunch |
| 12:00 – 14:30 | Exhibits |
| 12:00 – 13:30 | Lunchtime Satellite Symposium Supported by an unrestricted educational grant from MERZ. |
| 12:00 – 14:30 | Poster Session |
| Participants will break into separate groups for Basic Science, Clinical, Workshops A, and Workshops B. | |
| Parallel Track I (Basic Science) | |
| 14:30 – 18:30 | Genetics and Evolution Chair: Cesare Montecucco (Italy) |
| 14:30 – 15:00 | Regulation of C. Botulinum Growth and Toxin Production Miia Lindström (Finland) |
| 15:00 – 15:30 | Botulinum Neurotoxin Homologs in Non-Clostridial Species Andrew Doxey (Canada) |
| 15:30 – 16:00 | Two Selected Abstracts |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Molecular Interactions I Chair: Giampietro Schiavo (UK) |
| 16:30 – 17:00 | Binding of BoNT to Gycosylated SV2 Stefan Mahrhold (Germany) |
| 17:00 – 17:30 | Botulinum Neurotoxin Type A Enters a Non-Recycling Pool of Synaptic Vesicles Fredric Meunier (Australia) |
| 17:30 – 18:00 | Models of Drug-Induced Epileptiform Synchronization in Vitro: How Does Epileptic Activity Spread? Jordi Molgo (UK) |
| 18:00 – 18:30 | Translocation and Dissemination to Target Neurons of Botulinum Neurotoxin Type B in the Mouse Intestinal Wall Michael Popoff (France) |
| 18:30 – 20:00 | INA Business Meeting |
| 20:00 – 22:30 | Faculty Dinner |
| Clinical Tracks 1A & 1B |
|
| 14:30 – 16:00 | Oromandibular Dystonia Chair: Cindy Comella (USA) |
| 14:30 – 15:00 | Pathophysiology and Clinical Features Ryuji Kaji (Japan) |
| 15:00 – 15:30 | Systematic Review of BoNT Treatment Cindy Comella (USA) |
| 15:30 – 16:00 | Practical Tips for BoNT Treatment |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Urological Use of BoNT Chair: TBD |
| 16:30 – 17:00 | Overactive Bladder Management Strategy and Role of BoNT |
| 17:00 – 17:30 | Emerging Applications of BoNT to Treat Pelvic Pain Syndromes Christopher Smith (USA) |
| 17:30 – 18:00 | Update on BoNT Injections in Multiple Sclerosis and Interstitial Cystitis/Bladder Pain Syndrome Patients Francisco Cruz (Portugal) |
| Clinical Tracks 2A & 2B | |
| 14:30 – 16:00 | Lifespan Management of Muscle Activity in Cerebral Palsy (CP) Chair: Katharine Alter (USA) |
| 14:30 – 15:00 | Management of Pediatric Cerebral Palsy Florian Heinen (Germany) |
| 15:00 – 15:30 | Management of Adolescents/Teens |
| 15:30 – 16:00 | Transition and Management of Adults Cindy Ivanhoe (USA) |
| Clinical Workshops 1A & 1B | |
| 14:30 – 18:00 | Cosmetic Uses I Chair: Jean Carruthers (Canada) |
| 14:30 – 15:00 | Introduction to the Anatomy of Facial Aesthetics Jonathan Sykes (USA) |
| 15:00 – 15:30 | Evidence-Based Review of BoNT Injections for Aesthetic Use |
| 15:30 – 16:00 | BoNT Injections for Glabellar Frown Lines and Crow’s Feet Lines Jean Carruthers (Canada) |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Cosmetic Uses Injection Workshop with Live Patients Master Injector: Juan Sopena (Spain) |
| Clinical Workshops 2A & 2B | |
| 14:30 – 18:00 | Hand Dystonia Chair: Mark Hallett (USA) |
| 14:30 – 15:00 | Pathophysiology and Therapy Other Than BoNT Kirsten Zeuner (Germany) |
| 15:00 – 15:30 | Review of Clinical Trials Condrin Lungu (USA) |
| 15:30 – 16:00 | Muscle Selection for BoNT |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Hand Dystonia Injection Workshop with Live Patients |
| Clinical Workshops 3A & 3B |
|
| 14:30 – 18:00 | Hemifacial Spasm and Blepharospasm Chair: Raymond Rosales (Philippines) |
| 14:30 – 15:00 | Applying Tailored Assessment Scales in BoNT Injections |
| 15:00 – 15:30 | A Review of Evidence of BoNT Treatment Raymond Rosales (Philippines) |
| 15:30 – 16:00 | Practical Tips for BoNT Treatment |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Hemifacial Spasm and Blepharospasm Injection Workshop with Live Patients Master Injector: Francisco Grandas (Spain) |
| Clinical Workshops 4A & 4B |
|
| 14:30 – 18:00 | Cervical Dystonia Chair: Buz Jinazz (USA) |
| 14:30 – 15:00 | Review of Long-Term Studies and Registries Buz Jinazz (USA) |
| 15:00 – 15:30 | What are the Obstacles to Optimal Patient Outcomes? |
| 15:30 – 16:00 | Strategies to Increase Patient-Perceived Benefit Joseph Tsui, (Canada) |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Cervical Dystonia Injection Workshop with Live Patients |
| Friday, 20 January, 2017 | |
| Plenary Session |
|
| 08:30 – 09:00 | Evidence on BoNT in Selected Disorders David Simpson (USA) |
| 09:00 – 09:30 | The Booming Number of Novel Botulinum Neurotoxins: A Pandora’s Box of Novel Properties Eric Johnson (USA) |
| 09:30 – 10:00 | Potential New Uses of BoNT Injections in Movement Disorders Joseph Jankovic (USA) |
| 10:00 – 10:30 | Break |
| 10:30 – 11:00 | The Binding of BoNT to Different Peripheral Neurons Ornella Rossetto (Italy) |
| 11:00 – 11:30 | Central Effects of BoNT Matteo Caleo (Italy) |
| 11:30 – Noon | BoNT for Pain Syndromes Bahman Jabbari (USA) |
| Parallel Track I (Basic Science) | |
| 14:30 – 18:30 | Molecular Interaction II Chair: Mauricio Montal (USA) |
| 14:30 – 15:00 | Botulinum Toxin A Complex Exploits Intestinal M Cells to Enter the Host and Exert Neurotoxicity Yukako Fujinaga (Japan) |
| 15:00 – 15:30 | Two Selected Abstracts |
| 15:30 – 16:00 | Two Selected Abstracts |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Novel BoNTs and Toxin Engineering Chair: Sabine Pellett (USA) |
| 16:30 – 17:00 | Structural and Functional Insights Into the Interaction of BoNT/A Light Chain With SNAP-25 and SNAP-23 Thomas Binz (Germany) |
| 17:00 – 17:30 | Two Selected Abstracts |
| 17:30 – 18:00 | Non-Paralytic BoNTs for Pain Control Bazbek Davletov (UK) |
| 18:00 – 18:30 | Targeted Delivery of a SNARE Protease to Sensory Neurons Using a Single Chain Antibody (scFv) Against the Extracellular Domain of P2X(3) Inhibits the Release of a Pain Mediator Richard O’Kennedy (Ireland) |
| Clinical Tracks 1A & 1B |
|
| 14:30 – 16:00 | Spasmodic Dysphonia Chair: Andrew Blitzer (USA) |
| 14:30 – 15:00 | Pathology and Treatment Effects in Spasmodic Dysphonia |
| 15:00 – 15:30 | Long-Term Experience With BoNT for Spasmodic Dysphonia Andrew Blitzer (USA) |
| 15:30 – 16:00 | Research Priorities in Spasmodic Dysphonia |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Other Neurological Uses Chair: Francisco Cardoso (Brazil) |
| 16:30 – 17:00 | BoNT in Parkinsonism: The When, How, and Which for BoNT Injections Francisco Cardoso (Brazil) |
| 17:00 – 17:30 | Tremors: The When, How, and Which for BoNT Injections |
| 17:30 – 18:00 | Tics: The When, How, and Which for BoNT Injections Peter Moore (UK) |
| Clinical Workshops 1A & 1B | |
| 14:30 – 16:00 | Headache and Facial Pain Chair: TBD |
| 14:30 – 15:00 | Who Benefits Most? Predictors of Treatment Response |
| 15:00 – 15:30 | Can Treatment be Stopped Successfully in “Super Responders”? |
| 15:30 – 16:00 | Technical Aspects of the Use of BoNT for Treatment of Chronic Migraine |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Headache and Facial Pain Injection Workshop with Live Patients |
| Clinical Workshops 2A & 2B | |
| 14:30 – 18:00 | Cosmetic and Dermatologic Uses II Chair: Ellen Gendler (USA) |
| 14:30 – 15:00 | Aesthetic BoNT Injections of the Face: Options and Outcomes Ellen Gendler (USA) |
| 15:00 – 15:30 | BoNT Injections for Hyperhidrosis: Technical Pearls Dee Anna Glaser (USA) |
| 15:30 – 16:00 | Hyperhidrosis: Sympathectomy or BoNT Injections? |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Cosmetic and Dermatologic Uses II Injection Workshop with Live Patients Master Injector: Juan Sopena (Spain) |
| Clinical Workshop 3A & 3B | |
| 14:30 – 18:00 | Spasticity Chair: TBD |
| 14:30 – 15:00 | Pathophysiology, Assessment, and Goal Setting in Treatment of Spasticity |
| 15:00 – 15:30 | Botulinum Toxin in the Treatment of Upper Extremity Spasticity |
| 15:30 – 16:00 | Botulinum Toxin in the Treatment of Lower Extremity Spasticity Alberto Esquenazi (USA) |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Spasticity Injection Workshop with Live Patients |
| Clinical Workshops 4A & 4B | |
| 14:30 – 18:00 | Techniques for Localizing Muscles for BoNT Injections Chair: Marina de Koning-Tijssen (Amsterdam) |
| 14:30 – 15:00 | EMG/Electrical Stimulation Marina de Koning-Tijssen (Amsterdam) |
| 15:00 – 15:30 | Ultrasound Katharine Alter (USA) |
| 15:30 – 16:00 | Other Techniques Erle Lim (Singapore) |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Lifespan Management of Muscle Activity in Cerebral Palsy Injection Workshop with Live Patients Master Injector: Ignacio Pascual Pascual (Spain) |
| Saturday, January 21, 2017 | |
| General Session | |
| 08:30 – 8:45 | Poster Awards |
| 08:45 – 09:00 | Poster Awards |
| 09:00 – 9:20 | Controversy – PRO BoNT for Headache: PREEMPT vs. Individualized Treatment |
| 09:20 – 09:40 | Controversy – CON BoNT for Headache: PREEMPT vs. Individualized Treatment |
| 09:40 – 10:20 | TeNT Uptake and Transport Giampietro Schiavo (UK) |
| 10:20 – 10:30 | Closing Remarks |
| 10:30 – 11:00 | Break |
| Parallel Track I (Basic Science) | |
| 11:00 – 13:30 | Basic Science Track Detection and Protection Chair: Markus Kalkum (USA) |
| 11:00 – 11:30 | CMAP for Quantitative Detection of BoNTs Yasushi Torii (Japan) |
| 11:30 – Noon | Two Selected Abstracts |
| Noon – 12:30 | Endopep-MS and Hc-Based Neutralizing Oligoclonal Antibody Mixture |
| 12:30 – 13:00 | Outcome of the ANTIBOTABE mAB Development Project Michael Hust (Germany) |
| 14:00 – 15:00 | Incoming INA Board Meeting |
| 19:00 – 22:00 | Corporate Social Events |
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Click here for the Lunchtime Symposia schedule.
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Basic Science Sessions |
Genetics and Evolution
|
Molecular Interactions I
|
Molecular Interactions II
|
Novel BoNTs and Toxin Engineering
|
Detection of and Protection Against Botulinum Toxins
|
Clinical Sessions |
Cervical Dystonia
|
Cosmetic and Dermatologic Use – I
|
Cosmetic and Dermatologic Use – II
|
Hand Dystonia
|
Headache and Facial Pain
|
Hemifacial Spasm and Blepharospasm
|
Oromandibular Dystonia
|
Other Neurological Uses
|
Spasmodic Dysphonia
|
Spasticity
|
Cerebral Palsy |
Techniques for Localizing Muscles for BoNT Injections
|
Urological Use of BoNT
|
Workshops |
|
