| Wednesday, January 14, 2015 | |
| All Day | Exhibit Setup |
| 10:00 – 19:00 | Registration Open |
| 10:00 – 19:00 | Poster Setup |
| 18:30 – 19:30 | INA Current Board of Directors Meeting |
| 19:30 – 21:30 | Welcome Reception |
| Thursday, January 15, 2015 | |
| 07:00 – 18:30 | Registration/Information |
| 07:00 – 08:30 | Exhibits |
| Plenary Session – Mechanisms of Action | |
| 08:30 – 08:45 | Welcome and Opening Remarks Alberto Albanese (Milan, Italy) Mark Hallett (Bethesda, MD, USA) |
| 08:45 – 09:45 | Keynote Presentation – Acetylcholine Release |
| 09:45 – 10:20 | Explanation of Timing of Botulinum Neurotoxin BoNT Effects, Onset and Duration, and Clinical Ways of Influencing Them |
| 10:20 – 10:50 | Break |
| 10:50 – 11:25 | BoNT Complexes and Their Journey Toward the Nervous System |
| 11:25 – 12:00 | Clinical Comparison of Effects at Neuromuscular Junction, Autonomic Nerves, Pain and Enteric Nerves |
| 12:00 – 13:45 | Exhibits and Lunch |
| 12:00 – 13:30 | Satellite Symposium – MERZ LUNCH |
| 12:00 – 14:30 | Poster Session |
| The program will break into separate groups for Basic Science, Clinical, Workshop A, Workshop B, Workshop C, and Workshop D. | |
| Parallel Track I (Basic Science) | |
| 14:30 – 15:45 | Genetics and Evolution |
| 15:45 – 16:15 | Break |
| 16:15 – 18:15 | Molecular Interactions |
| Parallel Track I (Clinical) | |
| 14:30 – 16:00 | Initial and Subsequent Injections: How Do We Modify Approach to Optimize Outcomes? |
| 14:30 – 15:00 | Cervical Dystonia |
| 15:00 – 15:30 | Writer’s Cramp |
| 15:30 – 16:00 | Blepharospasm |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Measuring Outcomes of BoNT Therapy for Dystonia |
| 16:30 – 17:00 | Development of a Rating Scale |
| 17:00 – 17:30 | Focal Dystonia – Rating Scales |
| 17:30 – 18:00 | Spasticity – Rating Scales |
| Parallel Track II (Clinical) |
|
| 14:30 – 16:00 | Application of BoNT for the Treatment of Cerebral Palsy |
| 14:30 – 15:00 | Evidence-Based Review of Safety and Efficacy in Cerebral Palsy |
| 15:00 – 15:30 | Optimizing Outcomes With Adjunctive Therapy |
| 15:30 – 16:00 | Special Considerations – Dosing Limits |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Approach to Spasticity Using Botulinum Toxin |
| 16:30 – 17:00 | Management of Spasticity – Where Does BoNT Fit? |
| 17:00 – 17:30 | Maximizing Outcomes in Spasticity Using BoNT |
| 17:30 – 18:00 | Adjunctive Treatments for Spasticity |
| Parallel Track – Clinical (Workshop A) | |
| 14:30 – 18:30 | Treatment of Laryngeal Disorders and Oromandibular Dystonia |
| 14:30 – 15:00 | Evidence-Based Review: Abductor, Adductor, Vocal Tremor |
| 15:00 – 15:30 | Techniques of Injection Localization and Dosing |
| 15:30 – 16:00 | Oromandibular Dystonia |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Demonstrations on Video and Live Patients |
| Parallel Track – Clinical (Workshop B) | |
| 14:30 – 18:30 | Use of BoNT for Bladder Conditions |
| 14:30 – 15:00 | Functional Anatomy of the Genitourinary Tract |
| 15:00 – 15:30 | Introduction to Use of Botulinum Toxin for Genitourinary Conditions (Which Conditions, What Evidence?) |
| 15:30 – 16:00 | Injection Techniques |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Video and Pelvic Model Demonstrations |
| Parallel Track – Clinical (Workshop C) | |
| 14:30 – 18:30 | Cosmetic Uses of Botulinum Toxin |
| 14:30 – 15:00 | Introduction to the Anatomy of Facial Aesthetics |
| 15:00 – 15:30 | BoNT Injections of the Face: Efficacy and Side Effects |
| 15:30 – 16:00 | BoNT Injections for Hyperhidrosis: Efficacy and Side Effects |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Demonstrations on Video and Live Patients |
| Parallel Track – Clinical (Workshop D) | |
| 14:30 – 18:00 | Techniques for Localizing Muscles for BoNT Injection: Demonstration Workshop |
| 14:30 – 15:00 | EMG |
| 15:00 – 15:30 | Ultrasound |
| 15:30 – 16:00 | Other Techniques, Including Inspection, Palpation, Anatomic Landmarks |
| 16:00 – 16:30 | Break |
| 16:30 – 18:00 | Treatment of Tremor With BoNT |
| 16:30 – 17:00 | Approach to Hand Tremors |
| 17:00 – 17:30 | Head Tremor |
| 17:30 – 18:00 | Voice Tremor |
| 19:30 – 21:30 |
Faculty Dinner |
| Friday, January 16, 2015 | |
| 07:00 – 18:30 | Registration/Information |
| 07:00 – 08:30 | Exhibits |
| Plenary Session – The Botulinum Neurotoxins | |
| 08:30 – 09:10 | Structure of the BoNT/A Receptor Complex |
| 09:10 – 09:45 | Differences in Mode of Action of the Different Toxins |
| 9:45 – 10:20 | Clinical Differences Between Type A and B Toxins |
| 10:20 – 10:50 | Break |
| 10:50 – 11:25 | Clinical Differences Between A1 and A2 Toxins |
| 11:25 – 12:00 | Ganglioside Trafficking and Antiganglioside Antibodies |
| 12:00 – 13:45 | Exhibits and Lunch |
| 12:00 – 13:30 | Satellite Symposium (Lunch) |
| 12:00 – 14:30 | Poster Session |
| The program will break up into separate groups for Basic Science, Clinical, Workshop A, Workshop B, Workshop C, and Workshop D. | |
| Parallel Track I (Basic Science) | |
| 14:30 – 16:00 | Toxin Traffic |
| 16:00 – 16:30 | Break |
| 16:30 – 17:30 | Immunity and Immunoprotection |
| 17:30 – 18:30 | Toxin Detection |
| Parallel Track I (Clinical) | |
| 14:30 – 16:00 | Clinical Pearls: Optimizing Outcomes in Blepharospasm and Hemifacial Spasm |
| 14:30 – 15:00 | Diagnosis of Blepharospasm: Are We There Yet? |
| 15:00 – 15:30 | Is There One Toxin/Dose That is Superior to Another for Blepharospasm/Hemifacial Spasm (HFS)? |
| 15:30 – 16:00 | How to Inject for Optimal Outcome |
| 16:00 – 16:30 | Break |
| 16:30 – 17:00 | Platform Session- Long-Term Studies of BoNT Efficacy/Safety and Responsiveness |
| 16:30 – 18:30 | Considerations When Botulinum Toxin Treatment is Not Effective |
| 17:00 – 17:30 | The Many Causes of Secondary Nonresponse |
| 17:30 – 18:00 | Molecular Basis of Immunogenicity to Botulinum Neurotoxins |
| 18:00 – 18:30 | Role of Antibodies in Secondary Nonresponse |
| Parallel Track II Clinical |
|
| 14:30 – 16:030 | GAIT Lab: Functional Evaluation of Gait for Muscle Selection in Spasticity Patients: |
| 14:30 – 15:00 | Gait Analysis Methodology |
| 15:00 – 15:30 | Effects of Botulinum Toxin Treatment on Dystonic, Spastic Gait |
| 15:30 – 16:00 | Effects of Botulinum Treatment on Freezing Gait |
| 16:00 – 16:30 | Break |
| 16:30 – 17:00 | Platform Presentations: Use of BoNT in Nondystonic Disorders |
| 16:30 – 18:30 | Botulinum Toxin in Nondystonic Disorders |
| 17:00 – 17:30 | Botulinum Toxin for Psychogenic Movement Disorders |
| 17:30 – 18:00 | Tremor: Essential Tremor and Palatal Tremor |
| 18:00 – 18:30 | Parkinson Disease Clinical Aspects That Can Be Treated With Botulinum Toxin |
| Parallel Track (Workshop A) | |
| 14:30 – 16:30 | Botulinum Toxin for Headache |
| 14:30 – 15:00 | Evidence-Based Review of BoNT for Headache |
| 15:00 – 15:30 | Mechanism of Effect in Headache |
| 15:30 – 16:00 | Clinical Pearls for Optimal Outcome |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Case Studies: Techniques of Injection for Headache; Live Patients and Models |
| Parallel Track (Workshop B) | |
| 14:30 – 16:00 | Controversies and Unresolved Issues in Use of BoNT-1 |
| 14:30 – 15:00 | Esophageal Motility Disorders |
| 15:00 – 15:30 | Use of BoNT in Management of Piriformis Syndrome |
| 15:30 – 16:00 | Use of BoNT in Tic Disorders |
| 16:00 – 16:30 | Break |
| 16:30 – 17:00 | Platform Session – Use of BoNT in Nondystonic Disorders |
| 16:30 – 18:30 | Controversies and Unresolved Issues in Use of BoNT-2 |
| 17:00 – 17:30 | Camptocormia |
| 17:30 – 18:00 | Pain Other Than Headache |
| 18:00 – 18:30 | Anterocollis |
| Parallel Track (Workshop C) | |
| 14:30 – 18:30 | Treatment of Focal, Task-Specific Dystonias |
| 14:30 – 15:00 | Musician’s Dystonia |
| 15:00 – 15:30 | Writer’s Cramp |
| 15:30 – 16:00 | Laryngeal Dystonia |
| 16:00 – 16:30 | Break |
| 16:30 – 18:30 | Video Demonstrations |
| Parallel Track (Workshop D) | |
| 14:30 – 18:30 | Practical Applications for Cervical Dystonia, Blepharospasm, and Spasticity |
| 14:30 – 15:15 | Spasticity |
| 15:15 – 16:00 | Cervical Dystonia/Blepharospasm |
| 16:00 – 16:30 | Break |
| 16:30 – 17:15 | Spasticity |
| 17:15 – 18:00 | Cervical Dystonia/Blepharospasm |
| 18:00 – 18:30 | Panel for Q&A |
| Saturday, January 17, 2015 | |
| 07:00 – 12:30 | Registration / Information /Exhibits |
| 07:30 – 09:00 | INA Business Meeting |
| Plenary Session – The Future | |
| 09:00 – 09:30 | Depression |
| 09:30 – 10:00 | Pain, Sensory System, Central Effects |
| 10:00 – 10:30 | Shortened Intervals Between Injections |
| 10:30 – 11:00 | Break |
| 11:00 – 11:30 | Gaps in Basic Knowledge |
| 11:30 – 12:00 | Long-term Clinical Effects |
| 12:00 – 12:15 | Closing Remarks |
| 12:30 – 13:30 | Satellite Symposium Lunch |
