Abstract Committee Review

This abstract is well written, with a clear objective, strong dataset, and relevant outcomes for clinical practice. It convincingly demonstrates that earlier BoNT-A intervention after stroke leads to better functional goal attainment, an important message for optimizing spasticity care.

Strengths:

• Solid multicenter pooled dataset with nearly 1,000 patients.
• Clear and clinically meaningful primary endpoint (GAS-T).
• Transparent reporting of secondary outcomes and safety.

Areas for Minor Revision:

1. Clarify the Mechanistic Rationale: Add one brief line explaining why early BoNT-A use may improve outcomes (e.g., prevention of maladaptive neuroplasticity or secondary contracture).
2. Refine the Conclusion: End with a forward-looking statement linking early intervention to long-term functional recovery and rehabilitation efficiency.
   • Example: “Early intervention may enhance neuroplastic recovery and improve long-term rehabilitation outcomes.”
3. Balance Industry Disclosure: Consider briefly acknowledging that results derive from pooled company-sponsored studies but highlight clinical independence of analysis for transparency.