| Download Abstract: | 0040-Cosentino-Gastrointestinal-Disorders-rk.docx |
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| Abstract Title | Electromyography-Guided Unilateral Botulinum Toxin Injection for Retrograde Cricopharyngeus Dysfunction (R-CPD): Dose Effects, Sex Differences, and Clinical–Neurophysiological Correlates |
| First Author | Prof. Giuseppe Cosentino |
| Status | Approved |
| Comments to Author | This is a strong and well-structured abstract that effectively conveys the novelty and clinical relevance of the work. The study addresses an emerging indication—retrograde cricopharyngeus dysfunction—and provides prospective data on a sizeable cohort, which adds credibility and impact. The design is clear and pragmatic, with EMG-guided unilateral injections offering both mechanistic and clinical insights. The results are compelling, showing high efficacy rates, a clear dose–response effect, and meaningful improvements in symptoms and quality of life. The correlation between EMG parameters and treatment outcomes is particularly interesting, suggesting a valuable step toward individualized therapy and potential biomarkers for treatment response. The discussion of adverse effects is balanced and reassuring. Overall, this abstract presents an important contribution to a rapidly evolving field, combining sound methodology with clinically relevant findings. It will be of interest to both clinicians and researchers working with botulinum toxin and upper esophageal sphincter disorders. |
| Reviewer | Albrecht |