TOXINS 2026 Conference Program

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Wednesday, 14 January 2026
Wednesday, 14 January 2026
8:00 – 17:00 Poster Hall Setup
9:00 – 20:30 Registration Opens
12:00 – 16:00 TOXINS 101
18:00 – 19:30
Welcome and Opening Remarks
Lifetime Achievement Awards Presentation Ceremony
19:30 – 21:30
Welcome Reception
Poster and Exhibit Hall Open

 

Thursday, 15 January 2026
7:00 – 18:30 Registration/Information
7:30 – 8:30 Breakfast
Poster and Exhibit Hall Open
8:30 – 12:15
Plenary Session
Chair: Giampietro Schiavo, PhD, FMedSci, FRSB (UK)
8:30 – 8:45 Opening remarks and introduction of
keynote speaker
8:45 – 9:45 The uniqueness of the human neuron
Pierre Vanderhaeghen, MD, PhD (Belgium)
9:45 – 10:15 How BoNT/A enters the neuron: Understanding the mechanisms of translocation
Richard A. Kammerer, PhD (Switzerland)
10:15 – 10:55 Break
Poster and Exhibit Hall Open
10:55 – 11:45 Analog vs Digital
Using phenomenology and artificial intelligence/technology in the diagnosis of hyperkinetic movement disorders and its phenotypes
Moderator: Joseph Jankovic, MD (USA)

Phenomenology (video-case based)
Jörg Wissel, MD, FRCP (Germany)

Dx Incorporating Artificial Intelligence (AI)
Chi Wang Ip, MD (Germany)
11:45 – 12:15 Pathophysiology of muscle changes in patients with spasticity (including myopathy)
Rajiv Reebye, MD, FRCPC (Canada)
12:15 – 13:35 Lunch
12:15 – 14:15 Break
Poster and Exhibit Hall Open

 

Time Basic Science Track
Time Clinical Track 1A
Time Clinical Track 2A
Time Clinical Track 3A
Time Clinical Track 4A
Time Clinical Track 5A
Time Clinical Track 6A Time Clinical Track 7A
Time Clinical Track 8A
   
14:15 – 15:45 BoNT-Complex Architecture and Novel BoNT-Like Toxins
Chair:
14:15 – 15:45 Adult Spasticity I
Chair: Alberto Esquenazi, MD (USA)
14:15 – 15:45 Aesthetics and Dermatology I
Chair: Doris Hexsel, MD (Brazil)
14:15 – 15:45 Hot Topics in BoNT Therapy
Chair: Cynthia Comella, MD (USA)
14:15 – 15:45 Sialorrhea
Chair: Wolfgang Jost, MD (Germany)
14:15 – 15:45 Use of BoNTs in Urology/Gastroenterology
Chair: Dudley Robinson, MBBS, MD, FRCOG (UK)
14:15 – 15:45 Ultrasound: Lower Limb
Chair: Katharine Alter, MD (USA)
14:15 – 15:15 Injection Demonstration Workshop:
Cervical Dystonia
Moderator: Hubert Fernandez, MD (USA)
Moderator: Alberto Albanese, MD (Italy)
14:15 – 15:15 Injection Demonstration Workshop:
Vocal Dystonia and Voice Disorders
Moderator: Andrew Blitzer, MD, DDS (USA)
   
14:15 – 14:35 BoNT exploit host proteases to boost their oral toxicity via activating OrfX/P47
Rongsheng Jin, PhD (USA)
14:15 – 14:55 A pragmatic approach to treating upper and lower limb spasticity
Jörg Wissel, MD, FRCP (Germany)
Bo Biering-Sørensen, MD, MPG (Denmark)
14:15 – 14:55 Where to inject botulinum toxin for aesthetics: An anatomical analysis
Nowell Solish, MD (Canada)
14:15 – 14:40 Dosage conversion among different BTX preparations: Is there pharmacological evidence?
Joaquim Ferreira, MD, PhD (Portugal)
14:15 – 14:40 Targeting the salivary glands with ultrasound guidance
14:15 – 14:35 Mechanism of action of botulinum toxin in the bladder
14:15 – 15:45 Barbara Karp, MD (USA)
Atul Patel, MD (USA)
Omar Khan, MD (Canada)
Panagiotis Kassavetis, MD, PhD(USA)
Ann Ly, MD (USA)
Emmanuel Akano, MD (USA)
Sebastian Schroeder, MD (Germany)
Klemen Grabljevec, MD (Slovenia)
Steffen Berweck, MD (Germany)
14:15 – 15:15 Local Injectors:
Juan Carlos Martinez-Castrillo, MD (Spain)
14:15 – 15:15 Local Injectors:
Pedro Garcia Ruiz, MD (Spain)
   
14:35 – 14:55 Structure of the complete 14-subunit botulinum neurotoxin B complex reveals a unique anchoring through the narrow central pore of HA70
Pål Stenmark, PhD (Sweden)
14:40 – 15:00 Clinical relevance of neutralizing antibodies
Philipp Albrecht, MD (Germany)
14:35 – 14:55 Management of refractory OAB
Dudley Robinson, MBBS, MD, FRCOG (UK)
14:55 – 15:15 M-PTC/HA70 complex structure
Jasmin Weisemann, PhD (Germany)
14:55 – 15:20 The long-term adherence challenge – analysis of a non-intervention of BoNT-A over more than 10 years
Jorge Jacinto, MD (Portugal)
14:55 – 15:20 Correcting asymmetries: Aesthetic botulinum toxin techniques in therapeutic patients
Alessandra Grassi Salles, MD, PhD (Brazil)
15:00 – 15:25 Adherence and dropout in BoNT therapy
David Simpson, MD (USA)
14:40 – 15:05 Dosing strategies and long-term use of botulinum toxin for the management of Sialorrhea
Heakyung Kim, MD (USA)
14:55 – 15:15 Use of botulinum toxin in the neurogenic population
Francisco Cruz, PhD (Portugal)
Time Clinical Track 7B – Part 1
Time Clinical Track 8B – Part 1
15:15 – 15:35 Identification of botulinum neurotoxin-like gene cluster in different microrganisms
Andrew C. Doxey, PhD (Canada)
15:20 – 15:45 Pain reduction with repeated injections of botulinum toxin A in upper limb spasticity: A longitudinal analysis from the ULIS-III Study
15:20 – 15:45 2 Selected Abstracts
15:25 – 15:35 Panel Discussion
15:05 – 15:30 Japanese multicenter study of incobotulinum toxin for sialorrhea
Noriko Nishikawa, MD (Japan)
15:15 – 15:35 Emerging roles for botulinum toxin in urology and urogyanecology
Christopher Chermansky, MD (USA)
15:15 – 15:45 Injection Demonstration Workshop:
Challenging BoNT Cases: Treating Patients with Multiple Conditions
Moderator: Hubert Fernandez, MD (USA)
Moderator: Robert Chen, MD (Canada)
15:15 – 15:45 Injection Demonstration Workshop:
Cranial Dystonia (Meige, Hemifacial Spasm and Blepharospasm)
Moderator: Marie Vidailhet, MD (France)
15:35 – 15:45 1 Selected Abstract 15:30 – 15:45 1 Selected Abstract 15:35 – 15:45 Panel Discussion (Q&A)
15:15 – 15:45 Local Injectors:
15:15 – 15:45 Local Injectors:
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:25 Break
Poster and Exhibit Hall Open
15:45 – 16:15 Break
Poster and Exhibit Hall Open
15:45 – 16:15 Break
Poster and Exhibit Hall Open
15:45 – 16:15 Break
Poster and Exhibit Hall Open
Time Basic Science Track
Time Clinical Track 1B
Time Clinical Track 2B
Time Clinical Track 3B
Time Clinical Track 4B
    Time Clinical Track 6B
Time Clinical Track 7B – Part 2
Time Clinical Track 8B – Part 2
Time Clinical Track 9B
16:25 – 18:00 Structural and Functional Aspects of Clostridial Neurotoxins
Chair:
Co-Chair:
16:25 – 17:55 Pediatric Spasticity (and Other Conditions for BoNT Relative to the Pediatric Patient)
Chair:
16:25 – 17:55 Aesthetics & Dermatology Workshop II
Chair: Nowell Solish, MD (Canada)
16:25 – 17:55 Tics and Tremor
Chair: Joseph Jankovic, MD (USA)
16:25 – 17:55 Spasticity II
Chair: Jörg Wissel, MD, FRCP (Germany)
    16:25 – 17:55 Ultrasound Workshop: Upper Limb
Chair: Katharine Alter, MD (USA)
16:15 – 16:45 Injection Demonstration Workshop:
Challenging BoNT Cases: Treating Patients with Multiple Conditions
Moderator: Hubert Fernandez, MD (USA)
Moderator: Robert Chen, MD (Canada)
16:15 – 16:45 Injection Demonstration Workshop:
Cranial Dystonia (Meige, Hemifacial Spasm and Blepharospasm)
Moderator: Marie Vidailhet, MD (France)
16:15 – 17:45 Injection Demonstration Workshop: Urology/Urogynecology
Moderator: Dudley Robinson, MBBS, MD, FRCOG (UK)
Moderator: Francisco Cruz, PhD (Portugal)
16:25 – 16:45 Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A
Atsushi Yamagata, PhD (Japan)
16:25 – 16:50 Update on the use of botulinum toxin in pediatric patients
Mark Gormley, MD (USA)
16:25 – 17:05 Voyage to Beauty and Wellness
Jean Carruthers, MD (USA)
16:25 – 17:05 Botulinum toxin for treating tic disorder: Case series presentation
Joseph Jankovic, MD (USA)
Heakyung Kim, MD (USA)
16:25 – 16:50 Botulinum toxin for post-stroke spasticity: Experience in the developing world
    16:25 – 17:55 Katharine Alter, MD (USA)
Atul Patel, MD (USA)
Omar Khan, MD (Canada)
Panagiotis Kassavetis, MD, PhD (USA)
Ann Ly, MD (USA)
Emmanuel Akano, MD (USA)
Sebastian Schroeder, MD (Germany)
Klemen Grabljevec, MD (Slovenia)
Steffen Berweck, MD (Germany)
Serdar Koçer, MD (Switzerland)
16:15 – 16:45 Local Injectors:
Araceli Alonso Cánovas MD, PhD (Spain)
16:15 – 16:45 Local Injectors:
Lola Martinez Perez, MD (Spain)
16:15 – 17:45 Local Injectors:
16:45 – 17:05 Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetams
Janine Brunner, PhD (Belgium)
17:05 – 17:25 Retrograde transport and membrane translocation at the ER
Frederic Bard, PhD (Singapore)
16:50 – 17:15 The special challenges of pediatric spasticity
Rajiv Reebye, MD, FRCPC (Canada)
17:05 – 17:35 TBD 16:50 – 17:15 Chronic vs acute spasticity in adults: What are the options to maximize treatment goals?
Cindy B. Ivanhoe, MD (USA)
Time Clinical Track 7C
Time Clinical Track 8C
17:25 – 17:45 The effect of inter-domain interactions on BoNT onset
17:15 – 17:40 Spasticity management through neurolysis and or minimally-invasive neuro-orthopedics – focus on the pediatric patient
Jonathan Bemporad, MD (Italy)
17:35 – 17:45 1 Selected Abstract 17:15 – 17:40 BoNT for essential tremor: New data from placebo-controlled trials
David Simpson, MD (USA)
17:15 – 17:40 Beyond BoNT: Other injectables and treatments for patients with spasticity
Omar Khan, MD, FRCPC (Canada)
16:45 – 17:45 Injection Demonstration Workshop:
Occupational and Focal Limb Dystonia (Musicians)
Moderator: Robert Chen, MD (Canada)
16:45 – 17:45 Injection Demonstration Workshop:
Headache & Pain
Moderator:
17:45 – 18:00 1 Selected Abstract
17:40 – 17:55 1 Selected Abstract
17:45 – 17:55 1 Selected Abstract 17:40 – 17:55 2 Selected Abstracts
17:40 – 17:55 1 Selected Abstract
16:45 – 17:45 Local Injectors:
Pedro Garcia Ruiz, MD (Spain)
16:45 – 17:45 Local Injectors:
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
    18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting
18:00 – 19:00
INA Business Meeting

 

Friday, 16 January 2026
7:00 – 18:30 Registration/Information
7:30 – 8:30 Breakfast
Poster and Exhibit Hall Open
8:30 – 12:00
Plenary Session
Chair:
8:30 – 8:45 Welcome Back
8:45 – 9:20 Neuroplasticity and the mechanisms of chronic pain
David Bennett, MD (UK)
9:20 – 9:50 Neurotoxins in the management of pain: Where are we and where are we going?
David Simpson, MD (USA)
9:50 – 10:20 Perineural BTX-A treatment – A new way of treating neuropathic pain?
Bo Biering-Sørensen, MD (Denmark)
10:20 – 11:00 Break
Poster and Exhibit Hall Open
11:00 – 11:30 A look into the future: BoNT in cancer therapy
Gustavo Ayala, MD (USA)
11:30 – 12:00 The clinical utility of botulinum toxin in wound healing (BoNT-A and BoNT-E)
David Ozog, MD (USA)
12:00 – 13:30 Lunch
12:00 – 14:00 Break
Poster and Exhibit Hall Open

 

Time Basic Science Track
Time Clinical Track 1A
Time Clinical Track 2A
Time Clinical Track 3A
Time Clinical Track 4A
Time Clinical Track 5A
Time Clinical Track 6A
Time Clinical Track 7A
   
14:00 – 15:30 Genetic and Engineering of BoNTs
Chair:
Co-Chair:
14:00 – 15:30 Aesthetics and Dermatology III
Chair: Nowell Solish, MD (Canada)
14:00 – 15:30 Cervical Dystonia
Chair: Raymond Rosales, MD, PhD (Philippines)
14:00 – 15:30 Selected Topics
Chair: Bo Biering-Sørensen, MD, MPG (Denmark)
14:00 – 15:30 Migraine and Headache
Chair: Cristina Tassorelli, MD (Italy)
  14:00 – 15:30 Hemifacial Spasm, Blepharospasm and Meige Syndrome
Chair: Francisco Cardoso, MD (Brazil)
14:00 – 15:30 Ultrasound of the Head and Neck
Chair: Katharine Alter, MD (USA)
14:00 – 15:30 Injection Demonstration Workshop: Adult Spasticity
Moderator: Anthony Ward, MBE, BSc, MD, FRCP (UK)
Moderator: Cindy B. Ivanhoe, MD (USA)
   
14:00 – 14:20 Insects as Natural Hosts, Vectors and Reservoirs of Botulinum Neurotoxin-Producing Clostridia
14:00 – 14:25 "Only Tox" for facial rejuvenation – how far can you get with botulinum toxin alone
Patricia Ogilvie, MD (Germany)
14:00 – 14:25 Anatomic structures in the neck: Targeting strategies for cervical dystonia – ultrasound and EMG
14:00 – 14:25 Is there a role for botulinum toxin in the management of paratonia?
Galit Kleiner, MD, FRCPC (Canada)
14:00 – 14:30 Have we learned anything new about the pathophysiology of migraine and headache?
Rami Burstein, PhD (USA)
14:00 – 14:25 Clinical presentation of cranial dystonia and common mimics
Hyder (Buz) Jinnah, MD, PhD (USA)
14:00 – 15:30 Katharine Alter, MD (USA)
Heakyung Kim, MD (USA)
Barbara Karp, MD (USA)
Atul Patel, MD (USA)
Omar Khan, MD (Canada)
Hubert Fernandez, MD (USA)
Panagiotis Kassavetis, MD, PhD (USA)
Ann Ly, MD (USA)
Emmanuel Akano, MD (USA)
Steffen Berweck, MD (Germany)
14:00 – 15:30 Local Injectors:
   
14:20 – 14:40 Development and Optimization of Genetic Manipulation Systems in Group I Clostridium botulinum
Sho Amatsu, PhD (USA)
14:25 – 14:50 Long-term effects of botulinum toxin
Doris Hexsel, MD (Brazil)
14:25 – 14:50 Duration of botulinum toxin efficacy in cervical dystonia clinical trials: A scoping review
Alberto Albanese, MD (Italy)
14:25 – 14:50 Case series of botulinum toxin management of paratonia

14:30 – 14:55 Botulinum toxin vs CGRP-targeting monoclonal antibodies: competition or synergy?
Patricia Pozo-Rosich, MD, PhD (Spain)
14:25 – 14:50 Comparison of botulinum toxin injection techniques: Approach to blepharospasm vs. hemifacial spasm
Débora Maia, MD (Brazil)
14:40 – 15:00 Targeted degradation of α-Synuclein using an evolved botulinum toxin protease
Thomas Binz, PhD (Germany)
14:50 – 15:15 Non-cosmetic uses of botulinum toxin in dermatology
Nowell Solish, MD (Canada)
15:00 – 15:10 1 Selected Abstract
15:15 – 15:30 1 Selected Abstract
14:50 – 15:15 Capturing the "yo-yo" effect of botulinum toxin therapy: An app-based patient-centered outcome tool to improve treatment outcomes in cervical dystonia
Sarah Pirio-Richardson, MD, FAAN (USA)
14:50 – 15:15 Incidence of Spasticity is high in prolonged disorders of consciousness (PDOC): Is there a role for botulinum toxin in the management of nursing, discomfort and pain?
Nathalie Draulans, MD (Netherlands)
14:55 – 15:20 Post-traumatic headache: Is there a role for botulinum toxin?
Lanfranco Pellesi, MD, PhD (Denmark)
14:50 – 15:15 The variable phenomenology of meige syndrome
15:10 – 15:20 1 Selected Abstract
15:20 – 15:30 1 Selected Abstract
15:15 – 15:30 1 Selected Abstract
15:15 – 15:30 1 Selected Abstract
15:20 – 15:30 1 Selected Abstract
15:15 – 15:30 1 Selected Abstract
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
15:30 – 16:15 Break
Poster and Exhibit Hall Open
Time Basic Science Track
Time Clinical Track 1B
Time Clinical Track 2B
Time Clinical Track 3B
Time Clinical Track 4B
    Time Clinical Track 6B
Time Clinical Track 7B
Time Clinical Track 8B
16:15 – 17:45 Detection and Countermeasures
Chair:
Co-Chair:
16:15 – 17:45 Pain
Chair: Nadine Attal, MD, PhD (France)
Chair: Bahman Jabbari, MD (USA)
16:15 – 17:45 Telehealth and Artificial Intelligence Techology and Devices: Striving to Improve Patient Care
Chair: Jorge Jacinto, MD (Portugal)
16:15 – 17:45 Focal Limb Dystonia and Tremor
Chair: Alberto Albanese, MD (Italy)
16:15 – 17:45 Oromandibular Dystonia and Spasmotic Dysphonia
Moderator: Andrew Blitzer, MD, DDS (USA)
    16:15 – 17:45 Ultrasound of the Head and Neck, Upper and Lower Limb
Chair: Katharine Alter, MD (USA)
16:15 – 17:45 Injection Demonstration Workshop: Spasticity and other Conditions in Pediatric Patients
Moderator: Florian Heinen, MD (Germany)
Moderator: Darcy Fehlings, MD (Canada)
16:15 – 17:45 Injection Demonstration Workshop: Aesthetics and Dermatology
Moderator: Steve Yoelin, MD (USA)
Moderator: Patricia Ogilvie, MD (Germany)
16:15 – 16.35 The degradation of botulinum neurotoxin light chains using PROTACs
Patrick McNutt, PhD (USA)
16:15 – 16.35 Placebo vs nocebo mechansims in treating pain: Implications for trials and clinical care
Katja Weich, MD (UK)
6:15 – 17:05 Telehealth strategies: Present and near-future realities to enhance patient centric care, adherence and outcomes
Isabel de Amorim, MD (Portugal)
Jorge Jacinto, MD (Portugal)
Bo Biering-Sørensen, MD (Denmark)
16:15 – 16:40 Ultrasound targeting for upper limb dystonia
Alexandre Kreisler, MD, PhD (France)
16:15 – 16:40 Oromandibular Dystonia: Diagnosis, management and injection techniques
Roongroj Bhidayasiri, MD (Thailand)
    16:15 – 17:45 Katharine Alter, MD (USA)
Heakyung Kim, MD (USA)
Barbara Karp, MD (USA)
Atul Patel, MD (USA)
Hubert Fernandez, MD (USA)
Panagiotis Kassavetis, MD, PhD (USA)
Ann Ly, MD (USA)
Emmanuel Akano, MD (USA)
Steffen Berweck, MD (Germany)
16:15 – 17:45 Local Injectors:
Maria del Mar Garcia Romero, MD (Spain)
16:15 – 17:45 Local Injectors:
Sofia Ruiz del Cueto, MD (Spain)
16:35 – 16:55 Novel European botulism antitoxin
Andreas Rummel, PhD (Germany)
16:35 – 16:55 Botulinum toxin for complex regional pain syndromes
Areerat Suputtitada, MD (Thailand)
16:40 – 17:05 Focus on musician’s dystonia
André Lee, MD (Germany)
16:40 – 17:05 EMG-guided treatment of spasmodic dysphonia
Nikita Kohli, MD (USA)
16:55 – 17:15 Neuronal membrane-derived nanodiscs for broad-spectrum neurotoxin detoxification
Liangfang Zhang, PhD (USA)
16:55 – 17:15 Botulinum toxin in the management of painful musculoskeletal pathologies and sports traumatology
Serdar Koçer, MD (Switzerland)
17:05 – 17:30 Artificial intelligence and high-tech tools to improve diagnosis and management of spasticity and movement disorders patients
Mandar Jog, MD (Canada)
17:05 – 17:30 Central plasticity effects of botulinum toxin in focal hand dystonia
Aparna Wagle Shukla, MD (USA)
17:05 – 17:30 Motor and phonic tics
Andrew Blitzer, MD, DDS (USA)
17:15 – 17:35 Intraneuronal delivery of VHHs to reverse BoNT intoxication
Shin-Ichiro Miyashita, PhD (Japan)
17:15 – 17:35 Neuropathic pain: an update on the utility of botulinum toxin
Nadine Attal, MD, PhD (France)
17:30– 17:45 1 Selected Abstract

17:30 – 17:45 1 Selected Abstract
17:30 – 17:45 1 Selected Abstract
17:35 – 17:45 1 Selected Abstract
17:35 – 17:45 Panel Discussion (Q&A)

 

Saturday, 17 January 2026
7:30 – 12:00 Information
7:30 – 8:30 Breakfast
Poster and Exhibit Hall Open
9:00 – 12:00
Plenary Session
Chair:
9:00 – 9:10 Welcome Back
9:10 – 10:00 Questions about BoNT you were afraid to ask
Moderator: David Simpson, MD (USA)
Giampietro Schiavo, PhD, FMedSci, FRSB (UK)
Nowell Solish, MD (Canada)
Katharine Alter, MD (USA)
Ornella Rossetto, PhD (Italy)
Bo Biering-Sørensen, MD, MPG (Denmark)
10:00 – 10:10 Best Clinical Abstract
10:10 – 10:20 Best Basic Science Abstract
10:20 – 10:50 Once upon a dish: The next frontier in engineering multicellular systems
András Lakatos, MD, PhD, MRCP (UK)
10:50 – 11:20
11:20 – 11:50
11:50 – 12:00 Closing Remarks

 

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